Clinical trials query results
From Health Canada
| Drug name | CTA protocol title | Medical condition | Study population | Trial status |
|---|---|---|---|---|
| [18F]SDM-8 / [18F]T807 / PSILOCYBIN | DOES PSILOCYBIN CHANGE SYNAPTIC VESICULAR DENSITY IN THE BRAINS OF PATIENTS WITH MILD COGNITIVE IMPAIRMENT | COGNITIVE IMPAIRMENT | ADULT FEMALE,ADULT MALE | ONGOING |
| PSILOCYBIN | THE SAFETY AND EFFICACY OF PSILOCYBIN IN PARTICIPANTS WITH TREATMENT-RESISTANT DEPRESSION (P-TRD) | DEPRESSION | ADULT FEMALE,ADULT MALE | CLOSED |
| PSILOCYBIN | THE EFFICACY AND TOLERABILITY OF PSILOCYBIN IN PARTICIPANTS WITH TREATMENT-RESISTANT DEPRESSION: A PHASE 2, RANDOMIZED FEASIBILITY STUDY | TREATMENT RESISTANT DEPRESSION | ADULT FEMALE,ADULT MALE | CLOSED |
| PSILOCYBIN | MICRODOSING PSYCHEDELICS TO IMPROVE MOOD: A RANDOMIZED CLINICAL TRIAL | DEPRESSION | ADULT FEMALE,ADULT MALE | ONGOING |
| PSILOCYBIN | A 24-WEEK, MULTICENTRE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP, PHASE 2 CLINICAL TRIAL TO EVALUATE EFFICACY AND SAFETY OF PSILOCYBIN-ASSISTED PSYCHOTHERAPY IN ADULTS WITH ALCOHOL USE DISORDER (AUD) | ALCOHOL USE DISORDER | ADULT FEMALE,ADULT MALE | ONGOING |
| PSILOCYBIN | EVALUATING THE EFFECT OF LENGTH OF TIME ON SELECTIVE SEROTONIN REUPTAKE INHIBITORS (SSRIS) ON THE RESPONSE TO PSILOCYBIN-ASSISTED THERAPY IN INDIVIDUALS WITH MILD-MODERATE MAJOR DEPRESSIVE DISORDER (MDD) | MAJOR DEPRESSIVE DISORDER | ADULT FEMALE,ADULT MALE | CLOSED |
| PSILOCYBIN | INVESTIGATING THE THERAPEUTIC EFFECT OF PSILOCYBIN IN TREATMENT-RESISTANT POST-TRAUMATIC STRESS DISORDER (PTSD) | POST-TRAUMATIC STRESS DISORDER | ADULT FEMALE,ADULT MALE | CLOSED |
| PSILOCYBIN | A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE-FINDING STUDY TO EVALUATE THE SAFETY, TOLERABILITY AND EFFICACY OF PSILOCYBIN IN ADULTS WITH POST-TRAUMATIC STRESS DISORDER (PTSD) | POST-TRAUMATIC STRESS DISORDER | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN | NEUROBIOLOGICAL EFFECTS OF PSILOCYBIN IN TREATMENT RESISTANT BIPOLAR DEPRESSION: AN EMOTIONAL-PROCESSING FMRI PILOT STUDY | BIPOLAR DEPRESSION | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN | PSILOCYBIN FOR PSYCHOLOGICAL AND EXISTENTIAL DISTRESS IN PALLIATIVE CARE: A MULTI-SITE, OPEN-LABEL, SINGLE ARM PHASE I/II PROOF-OF-CONCEPT, DOSE-FINDING, AND FEASIBILITY CLINICAL TRIAL | END OF LIFE DISTRESS | ADULT FEMALE,ADULT MALE | ONGOING |
| PSILOCYBIN | STANDARDIZED NATURAL PSILOCYBIN-ASSISTED PSYCHOTHERAPY FOR TAPERING OF OPIOID MEDICATION IN PATIENTS WITH CHRONIC PAIN: AN OPEN-LABEL FEASIBILITY STUDY | PAIN | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN | PSILOCYBIN ASSISTED THERAPY FOR ANXIETY AND MOOD DISORDERS: A TRANSDIAGNOSTIC OPEN LABEL CLINICAL TRIAL FOR IMPROVING WELL-BEING (PAM-WELL) | OBSESSIVE COMPULSIVE DISORDER,POST-TRAUMATIC STRESS DISORDER,MAJOR DEPRESSIVE DISORDER,ANXIETY DISORDER,BIPOLAR DISORDER | ADULT FEMALE,ADULT MALE | ONGOING |
| PSILOCYBIN | AN OPEN LABEL PRAGMATIC FEASIBILITY STUDY ON A RESILIENCE FOCUSED COMMUNITY OF PRACTICE PROGRAM WITH PSILOCYBIN-ASSISTED THERAPY (PAT) FOR END OF LIFE PATIENTS | END OF LIFE DISTRESS | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN | AN OPEN-LABEL INVESTIGATION OF THE EFFECTS OF SUB-PERCEPTUAL REPEAT DOSING OF PSILOCYBIN ON THE BEHAVIOURAL AND COGNITIVE SYMPTOMS OF FRAGILE X SYNDROME IN ADULT PATIENTS | FRAGILE X SYNDROME | ADULT FEMALE,ADULT MALE | ONGOING |
| PSILOCYBIN | A MASTER PROTOCOL TO EXAMINE THE IMPACT OF PSILOCYBIN (4-PHOSPHORYLOXY-N,NDIMETHYLTRYPTAMINE) IN ASSISTED GROUP THERAPY ON MEASURES OF WELLNESS | MENTAL HEALTH CONCERNS | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN | A 2-PART, PHASE 2A, RANDOMIZED, DOUBLE-BLIND TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, AND EFFICACY OF PSILOCYBIN ORAL SOLUTION IN ADULTS WITH GENERALIZED ANXIETY DISORDER | ANXIETY DISORDER | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN | PSILOCYBIN-ASSISTED EXISTENTIAL, ATTACHMENT AND RELATIONAL (PEARL) THERAPY FOR PATIENTS WITH ADVANCED CANCER: A PHASE II OPEN-LABEL TRIAL | DEPRESSION,CANCER | ADULT FEMALE,ADULT MALE | ONGOING |
| PSILOCYBIN | PSILOCYBIN-ASSISTED MASSED COGNITIVE PROCESSING THERAPY FOR CHRONIC POSTTRAUMATIC STRESS DISORDER: AN OPEN-LABEL TRIAL | POST-TRAUMATIC STRESS DISORDER | ADULT FEMALE,ADULT MALE | ONGOING |
| PSILOCYBIN | CONSCIOUS MIND'S STUDY TO EXAMINE THE IMPACT OF PSILOCYBIN (4-PHOSPHORYLOXY-N,N-DIMETHYLTRYPTAMINE) IN ASSISTED GROUP THERAPY ON MEASURES OF WELLNESS. | MENTAL HEALTH CONCERNS | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN | A PHASE 2A, PLACEBO-CONTROLLED RANDOMIZED, DOUBLE-BLIND TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, AND PRELIMINARY EFFICACY OF PSILOCYBIN ORAL SOLUTION IN ADULTS WITH GENERALIZED ANXIETY DISORDER | ANXIETY DISORDER | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN | GATHERING GROUP'S STUDY TO EXAMINE THE IMPACT OF PSILOCYBIN (4-PHOSPHORYLOXY-N,N-DIMETHYLTRYPTAMINE) IN ASSISTED GROUP THERAPY ON MEASURES OF WELLNESS. | MENTAL HEALTH CONCERNS | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN | PSILOCYBIN-ASSISTED EXISTENTIAL, ATTACHMENT AND RELATIONAL (PEARL) THERAPY FOR CAREGIVERS OF PATIENTS WITH ADVANCED CANCER: A PHASE II OPEN-LABEL TRIAL | DEPRESSION,ANXIETY DISORDER | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN | A REGISTERED CLINICAL TRIAL OF PSILOCYBIN-ASSISTED THERAPY (PAT) FOR STIMULANT USE DISORDER: A SAFETY, FEASIBILITY AND EFFICACY STUDY | SUBSTANCE ABUSE | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN | TREATMENT WITH PSILOCYBIN FOR CHRONIC NEUROPATHIC PAIN AND DEPRESSION (TRANSCEND): AN OPEN-LABEL CLINICAL TRIAL | NEUROPATHIC PAIN,TREATMENT RESISTANT DEPRESSION | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN | ENGAGING MOOD BRAIN CIRCUITS WITH PSILOCYBIN: A RANDOMIZED NEUROIMAGING TRIAL IN DEPRESSION | DEPRESSION | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN | PSILOCYBIN-ASSISTED THERAPY FOR CHRONIC TRAUMATIC BRAIN INJURY | TRAUMATIC BRAIN INJURY | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN (APEX-002-A01) | A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY, SAFETY AND TOLERABILITY OF PSILOCYBIN CAPSULE IN TREATING MODERATE DEPRESSION AMONG ADULTS WITH POST-TRAUMATIC STRESS DISORDER | POST-TRAUMATIC STRESS DISORDER | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN (APEX-002-A02) | A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE SAFETY, TOLERABILITY AND EFFICACY OF PSILOCYBIN-ASSISTED PSYCHOTHERAPY IN TREATING SEVERE DEPRESSION AMONG ADULTS WITH POST-TRAUMATIC STRESS DISORDER (PTSD) | DEPRESSION,POST-TRAUMATIC STRESS DISORDER | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN (COMP360) | A PHASE III, MULTICENTRE, RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO INVESTIGATE THE EFFICACY, SAFETY, AND TOLERABILITY OF A SINGLE ADMINISTRATION OF COMP360 IN PARTICIPANTS WITH TREATMENT-RESISTANT DEPRESSION | DEPRESSION | ADULT FEMALE,ADULT MALE | ONGOING |
| PSILOCYBIN (OPTI-PSIE) | A PHASE II STUDY ASSESSING THE EFFICACY OF PSILOCYBIN-ASSISTED PSYCHOTHERAPY WHEN ADMINISTERED TO FRONTLINE MENTAL HEALTHCARE WORKERS SUFFERING FROM MAJOR DEPRESSIVE DISORDER RELATED TO COVID-19 | MAJOR DEPRESSIVE DISORDER | ADULT FEMALE,ADULT MALE | ONGOING |
| PSILOCYBIN (PEX010) | PSILOCYBIN-ASSISTED PSYCHOTHERAPY FOR TREATMENT-RESISTANT DEPRESSION: A RANDOMIZED PHASE II CLINICAL TRIAL COMPARING ONE VERSUS TWO PSYCHEDELIC DOSES OF PSILOCYBIN (PSI-1V2) | DEPRESSION | ADULT FEMALE,ADULT MALE | ONGOING |
| PSILOCYBIN (PEX010) | MECHANISMS SUPPORTING PSILOCYBIN-ASSISTED PSYCHOTHERAPY FOR ALCOHOL USE DISORDER: A RANDOMIZED, CONTROLLED CLINICAL TRIAL | ALCOHOL USE DISORDER | ADULT FEMALE,ADULT MALE | ONGOING |
| PSILOCYBIN (PEX010) | OPEN-LABEL, SINGLE ARM STUDY OF PSILOCYBIN-ASSISTED THERAPY FOR OPIOID USE DISORDER: A FEASIBILITY STUDY | OPIOID USE DISORDER | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN (PEX010) | EVALUATING THE FEASIBILITY, CLINICAL EFFECTS, AND SAFETY OF PSILOCYBIN-ASSISTED PSYCHOTHERAPY FOR TREATMENT-RESISTANT OBSESSIVE-COMPULSIVE DISORDER: AN OPEN-LABEL CLINICAL TRIAL | OBSESSIVE COMPULSIVE DISORDER | ADULT FEMALE,ADULT MALE | ONGOING |
| PSILOCYBIN (PEX010) | PSILOCYBIN FOR TREATMENT-RESISTANT DEPRESSION IN AUTISM: A PILOT TRIAL WITH PRE-POST BRAIN AND COGNITIVE MEASUREMENT TO UNDERSTAND MECHANISMS (PAT-DA) | DEPRESSION | ADULT FEMALE,ADULT MALE | ONGOING |
| PSILOCYBIN (PEX010) | ASSESSING THE FEASIBILITY OF A PSYCHEDELIC-ASSISTED GROUP PROGRAM FOR DEPRESSION IN FIRST RESPONDERS (EMP_PSILO_002) | DEPRESSION | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN (PEX010) | TOWARD PATIENT-TAILORED CARE FOR TREATMENT-RESISTANT DEPRESSION: A PILOT PATIENT-PREFERENCE CLINICAL TRIAL OF PSILOCYBIN-ASSISTED PSYCHOTHERAPY | TREATMENT RESISTANT DEPRESSION | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN (PEX010) / DEXTROMETHORPHAN | PSILOCYBIN FOR ENHANCED ANALGESIA IN CHRONIC NEUROPATHIC PAIN: A RANDOMIZED CONTROLLED PILOT TRIAL (PEACE-PAIN) | NEUROPATHIC PAIN | ADULT FEMALE,ADULT MALE | PENDING |
| PSILOCYBIN / RISPERIDONE | DOES PSILOCYBIN REQUIRE PSYCHEDELIC EFFECTS TO TREAT DEPRESSION? A 4-WEEK, DOUBLE-BLIND, PROOF-OF-CONCEPT RANDOMIZED CONTROLLED TRIAL | TREATMENT RESISTANT DEPRESSION | ADULT FEMALE,ADULT MALE | ONGOING |
| PSILOCYBIN/ RISPERIDONE/ SDM-8 18F | IMAGING THE EFFECTS OF SEROTONIN 2A RECEPTOR MODULATION ON SYNAPTIC DENSITY IN TREATMENT-RESISTANT DEPRESSION (SYNVEST) | TREATMENT RESISTANT DEPRESSION | ADULT FEMALE,ADULT MALE | ONGOING |